A sweeping global study conducted with the participation of 30,000 individuals from India has unearthed a robust connection between frequent consumption of ultra-processed foods (UPFs) and a decline in mental well-being. The research uncovered that those who frequently indulged in UPFs throughout the day were nearly three times more likely to experience mental health challenges compared to those who rarely or never consumed such items.
This extensive global study, which encompassed 30,000 participants from India, suggests a substantial and concerning association between regular consumption of ultra-processed foods and a significant deterioration in mental well-being across different genders, age groups, and national backgrounds.
According to the findings of this study, individuals who consumed ultra-processed foods (UPFs) multiple times daily faced a nearly threefold higher risk of experiencing mental distress or struggling with their mental health compared to those who infrequently or never consumed such foods. These conclusions were drawn from the analysis of responses provided by nearly 300,000 individuals worldwide, as reported by a US-based nonprofit organization.
Ultra-processed foods, or UPFs, are broadly defined as food products manufactured on an industrial scale, typically including carbonated beverages, packaged chips and snacks, various confectionery items, and pre-packaged ready-to-eat meals.
Explaining the concept of UPFs, a neuroscientist stated, “There is some controversy on how to properly define UPFs. The simple rule of thumb is that if it contains ingredients you don’t have and processing that you can’t do in a home kitchen, then it probably qualifies.”
These findings hold particular significance given that India is one of the fastest-growing markets for ultra-processed foods. The World Health Organization (WHO) reports that the retail sales value of this sector in India witnessed a compound annual growth rate of 13.37% between 2011 and 2021. Over the next decade, UPFs are projected to outpace both India’s GDP growth and the increase in consumption of essential food items.
Previous studies have already linked UPFs to health conditions such as obesity, diabetes, and heart diseases, and some recent research has even suggested correlations with depression.
The current study, spanning 26 countries, delves deeper by revealing connections between these foods and a variety of mental health parameters.
The study examines a broad spectrum of symptoms on a continuum, suggesting that symptoms of depression worsen with increased UPF consumption while indicating a continuum of deterioration across all aspects of mental functioning, particularly the ability to regulate thoughts and emotions, as per a neuroscientist’s statement.
Among the 24 mental function parameters affected by UPF consumption, the study pinpointed that depression symptoms like feelings of sadness, distress, and hopelessness, as well as appetite regulation, were the most significantly impacted aspects for both males and females.

Furthermore, the study observed a consistent pattern of declining mental well-being with heightened UPF consumption across genders, income levels, and age groups, independent of exercise frequency.
“This suggests a causal relationship,” the study asserts. “The breadth and nature of symptoms suggest that ultra-processed food may mediate a widespread physiological dysregulation of mental processes. UPFs may contribute significantly to the mounting mental health challenges, especially among young adults aged 18-24, who are twice as likely to consume such foods daily compared to adults aged 45 and older,” the study underscores.
This research was part of the Global Mind Project conducted by Sapien Labs, which investigates mental well-being worldwide. The project employs an assessment known as the Mental Health Quotient, gathering data on 47 aspects of mental well-being, along with demographic, lifestyle, and life experience information. This data is available for use by academic and nonprofit research organizations.
While the study demonstrates a causal link between UPFs and mental health, it calls for further research into the mechanisms by which these foods affect the brain. “A societal shift towards less consumption of ultra-processed diets can therefore play a significant role in alleviating the burden on mental health,” the study concludes.